- Oliguria failing to respond to adequate doses of furosemide (doses up to 5 mg/kg may be needed in presence of renal impairment).
- Persistent renal impairment
- Persistent proteinuria
- Failure of complement levels to normalize by 8 weeks
Most children with acute post-infectious nephritis can be managed in the local hospital in consultation with the SPIN and paediatric nephrologists in Cardiff or Liverpool (for North Wales). It is unusual for these children to require renal replacement therapy. Please refer to the guideline endorsed by your lead paediatric nephrology centre.